The Fight Corneal Blindness! (FCB!) Project is a web-based registry designed to collect high quality outcomes data from patients in the clinical setting on the clinical effectiveness and safety of emerging therapies and surgical techniques on conditions that impair vision and cause blindness, such as keratoconus and corneal infection.
The FCB! Project is part of the Save Sight Registries and has key registries relating to corneal eye conditions.
By analysing ‘real life’ data collected by the system, and through a consultative and collaborative process, patients and other stakeholders are informed of the clinical effectiveness of the different types of treatment approaches for ocular diseases.
Through the user-friendly platform, patients can engage with their treatment plan and monitor the effectiveness of their treatment. A graph generated by the system summarises a patients treatment journey, helping them to understand the outcomes of their treatment. The system tracks patient visual acuity and features of their keratoconus at each visit against their treatment.
Keratoconus affects the eye by thinning the cornea, the eye’s window. The thinning causes the cornea to distort and bulge, becoming more cone-shaped, rather than the usual round shape. The end result can be significant loss of vision.
It affects 1 in every 2,000 people, with men and women equally affected. The exact cause is unknown. Initial symptoms are usually blurring and distortion of vision that may be corrected with glasses, and increased sensitivity to light. As the condition advances, vision may no longer be adequately corrected with glasses due to the high irregularity of the cornea.
Keratoconus typically affects both eyes but each eye may be affected differently. The condition causes severe visual impairment in 20% and as it typically affects young people has a significant public health impact.
The project will collect information regarding a particular treatment of keratoconus called cross-linking.
Cross-linking is a treatment aimed to prevent the progression of keratoconus. Cross-linking works by increasing collagen crosslinks in the cornea, which are the natural “anchors” within the cornea. These anchors are responsible for preventing the cornea from bulging out and becoming steep and irregular.
The cross-linking procedure involves saturating the cornea with riboflavin drops, which are then activated by ultraviolet light. This process increases the amount of collagen cross-linking in the cornea and strengthens the cornea.
The Ophthalmic Research Institute of Australia (ORIA) provided seed funding, along with a generous donation from Mr Larry Korhauser (President, Keratoconus Australia), in memory of his mother, for the establishment of the Keratoconus Registry. In-kind funding from the University of Sydney’s flagship Fight Retinal Blindness! Project and Sydney Eye Hospital has ensured the growth of the project.
The registry has a national steering committee composed of corneal experts.
|Chief Investigator:||Professor Stephanie Watson|
Telephone: +61 2 9389 0666
|Project Manager:||Dymow Barbosa|
|Registry information and support:||Email: SSI.SSR@sydney.edu.au|
Telephone: +61 2 9382 7304
Watson S, Gunnasekara G, Go C, Kerdraon Y, Males J, Daniell M, Chan E, Knecht-Bosch M, Herrera-Bond A, Weston C, Garcia M, Bathelmes D, Gillies M, Efficient capture of high-quality data on the outcomes for corneal cross-linking for keratoconus: The Fight Corneal Blindess Project. Clin Exp Ophthalmol. 2015. 43 (Suppl 1): 48.
Watson S, Go C, Gunnasekara G, Herrera-Bond A, Kerdraon Y, Males J. Corneal cross-linking at Sydney Eye Hospital: Pilot evaluation of the Fight
Corneal Blindness module for corneal cross-linking. Clin Exp Ophthalmol. 2015 43 (Suppl 1): 86.
Tan J, Watson S. A review of clinical registries in ophthalmology. Clin Exp Ophthalmol. 2016. 44:93.
Go C, Watson S, Kerdraon Y, Males J, Petsoglou C, Kim P, Ball M, Moloney G, Herrera-Bond A, Nguyen V, Dinh A, Garcia M, Gillies M. Outcomes of corneal cross-linking from a large tertiary referral eye care centre. Clin Exp Ophthalmol. 2016. 44:90
Watson S, Daniell M, Chan E, Kerdraon Y, Males J, Morlet N, Beckingsale P, Mills R, Go C, Barthelmes C, Knecht-Bosch M, Herrera-Bond A, Nguyen V, Dinh A, Weston C, Garcia M, Gillies M. The Keratoconus module of the Save Sight Registries for efficient capture of high-quality data on the outcomes of corneal cross-linking for keratoconus. Clin Exp Ophthalmol. 2016. 44: 47-48
Save Sight Registries: Making CPD easier! Stephanie Watson, Australian Society of Ophthalmologists Business Skills Expo 2017.
The outcomes of corneal cross-linking for Keratoconus form routine clinical practice across Australia and New Zealand: Results from the Save Sight Registries Keratoconus Module. Stephanie Watson, Mark Daniell, Elsie Chan, Yves Kerdraon, John Males, Nigel Morlet, Peter Beckingsale, Richard Mills, Chris Go, Daniel Barthelmes, Martina Knecht-Bosch, Amparo Herrera-Bond, Vuong Nguyen, Amanda Dinh, Courtney Weston, Marco Garcia, Mark Gillies. ARVO Baltimore USA 2017.
Tracking Treatment outcomes in Keratoconus: Save Sight Registries Keratoconus Module. Stephanie Watson. ARVO Asia, Brisbane 2017
Tracking Treatment outcomes in Keratoconus: Save Sight Registries Keratoconus Module. Stephanie Watson. APAO, Singapore 2017
Keratoconus Corneal Collagen cross-linking module. Stephanie Watson. ANZ Corneal Society, Brisbane 2017
The outcomes of corneal cross-linking for Keratoconus form routine clinical practice across Australia and New Zealand: Results from the Save Sight Registries Keratoconus Module. Stephanie Watson, Mark Daniell, Elsie Chan, Yves Kerdraon, John Males, Nigel Morlet, Peter Beckingsale, Richard Mills, Chris Go, Daniel Barthelmes, Martina Knecht-Bosch, Amparo Herrera-Bond, Vuong Nguyen, Amanda Dinh, Courtney Weston, Marco Garcia, Mark Gillies. RANZCO Annual Conference, Melbourne 2016
12 month outcomes of corneal cross-linking for Keratoconus from routine clinical practice across Australia and New Zealand: Results from Save Sight Registries Keratoconus module. Stephanie Watson, Chris Go, Yves Kerdraon, John Males, Mark Daniell, Elsie Chan, Martina
Knecht-Bosch, Amparo Herrera-Bond, Courtney Weston, Marco Garcia, Daniel Barthelmes, Mark Gillies. Rapid Fire Session. RANZCO Annual Conference, Melbourne 2016
Outcomes of corneal cross-linking from a large tertiary referral eye care centre. Go C, Watson SL, Yves Kerdraon, John Males, Con Petsoglou, Peter Kim, Matt Ball, Gerard Sutton, Greg Moloney, Amparo Herrera-Bond, Vuong Nguyen, Amanda Dinh, Marko Garcia, Mark Gilles. Poster session. RANZCO Annual Conference, Melbourne 2016
Orthoptists driving clinical improvements via the Save Sight Registries (SSR). Amanda Dinh, Amparo Herrera-Bond, Phuc Nguyen, Mark Gillies, Stephanie Watson. Orthoptics Australia conference 2016
Save Sight Registries. Watson SL. Business Skills Expo. Australian Society of Ophthalmologists. Sydney 2016
Corneal cross linking. 16th Malaysian Conjoint Meeting, Kuala Lumpar 2016
Corneal update. Watson SL. Synergeyes. Sydney 2016
Keratoconus Australia Information Session 2016 Presentation prepared by SSI, presented CERA Researcher Srujana Sahebjada
Efficient data capture of outcome data for corneal cross-linking. Watson SL. Poster. Gordon Research Corneal Conference. Ventura Beach, CA, USA 2016
Fight Corneal Blindness Project. Watson SL. Invited speaker. Corneal Society Melbourne 2016
Corneal Cross-linking: Just Do it? Watson SL. Invited speaker. ORIA symposium. RANZCO Annual Meeting, Wellington, New Zealand 2015
Corneal Cross-linking Audit. Watson SL. RANZCO Annual Meeting, Wellington, New Zealand 2015
Fight Corneal Blindness Project. Watson SL. RANZCO Annual Meeting, Wellington, New Zealand 2015
Keratoconus Australia Information Session Presentation 2015 prepared by SSI, presented CERA Dr Elsie Chan
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